One of the earliest signs is localized skin irritation. This may include:
- Redness or mild swelling at the bite area
- Itching or a rash that looks similar to a mosquito or bed bug bite
- A firm or slightly painful lump under the skin
- In many cases, these symptoms disappear within a few days, which is why they are often ignored.
Swelling Around the Eye (Romaña Sign)
One of the most recognizable early signs of Chagas infection is swelling around one eye, known medically as Romaña sign. This occurs when parasite-contaminated feces enter the eye after a bite near the face.
The eyelid may appear puffy, reddish, and inflamed, usually without much pain. While this sign does not appear in everyone, it is a strong indicator of early infection and requires immediate medical attention.
Flu-Like Symptoms That Seem Unrelated
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